LEVEL 1A EVIDENCE
Hyperthermia Treatment for
3 year survival rates more than doubled when hyperthermia (meHT) was combined with standard of care chemoradiation for locally advanced cervical cancer in South Africa.
The same EHY2000 device was used. The number of patients who were disease free at 3 years was 32% more in the hyperthermia group than in the chemoradiation group alone.
3 Years Disease Free Survival Rate %
Level 1 Evidence: Phase III clinical trial at Wits Donald Gordon
Minnaar CA, Maposa I, Kotzen JA, Baeyens A.
Effects of Modulated Electro-Hyperthermia (mEHT) on Two and Three Year Survival
of Locally Advanced Cervical Cancer Patients.
Cancers (Basel). 2022;14(656):1-20.
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In another randomised control trial with a 12 year long term follow up looking at hyperthermia in combination with Radiation Vs Radiation alone for locoregionally advanced cervical cancer; both disease control rates and survival rates almost doubled, 37% to 56%, and 20% to 37% respectively.
12 Years Follow Up Cervical Cancer %
Level 1 evidence: Van der Zee, J; González González, D.
The Dutch Deep Hyperthermia Trial: results in cervical cancer. International Journal of Hyperthermia.
2002, 18:1, 1-12, DOI: 10.1080/02656730110091919. Erratum in: Int J Hyperthermia. 2003 Mar- Apr;19(2):213. PMID: 11820462.
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