Hyperthermia
Re-Irradiation
Re-irradiation of Various Locally Recurrent Cancers Combined with Hyperthermia
*AMC protocol: re-irradiation with 8 fractions of 4Gy, (2 per week) + 1 hyperthermia /week
BVI protocol: re-irradiation with 12 fractions of 3Gy, (4 per week) + 2 hyperthermia / week
References: download PDF using button below
To know more download our PDF with the Abstract from Clinical Trials on Re-Irradiation
Irresectable, loco-regional recurrent breast cancers in previously irradiated areas. Hyperthermia combined with re-irradiation (reRT) (hypofractionated, low dose), two protocols are available internationally, both reporting similar results:
AMC protocol: re-irradiation with 8 fractions of 4Gy, (2 per week) + 1 hyperthermia /week
BVI protocol: re-irradiation with 12 fractions of 3Gy, (4 per week) + 2 hyperthermia / week
AMC protocol is the standard treatment in the Netherlands. AMC protocol shows a higher rate of toxicity than the BVI protocol.[3]
The BVI protocol is therefore recommended.
Outcomes
- Local response rate >60% in the absence of other options
HT plus Re-irradiation for Breast Cancer
References: download PDF using button below
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